All, Health and Wellbeing, Pain and Inflammation

CB2 – pain and inflammation miracle?


CB2 oil – What’s the story?

5 minute read

Got pain? Then this might be an interesting read.

1 in 5 Australians suffers debilitating pain and inflammation conditions that affect their day-to-day life. Unfortunately, the current medical treatment for pain relief is not suitable for so many. There are numerous side effects and risks associated with many of these treatments (i.e. the use of non-steroidal anti-inflammatory drugs, opioids, and anti-depressants). Thankfully there are good complementary and natural alternatives.

Emerging research on CB2 oil is promising to be a 100% natural pain-relieving and anti-inflammatory option.

So, here is a snapshot of the CB2 research thus far…

What is CB2?

β-Caryophyllene, more commonly known as CB2 is a plant oil extract.  CB2 is often sourced from the hemp plant which is also a rich source of terpenes, fat soluble vitamins and essential fatty acids. The anti-inflammatory benefits from CB2 are β-caryophyllene and β-myrcene. These are the compounds in plants that give them it’s flavour and smell.

How do the CB2 terpenes work?

These naturally occurring terpenes in CB2 attach to the C Beta-2 cannabinoid receptors which are found all over the body and specifically in the brain. CB2 receptors are responsible for regulating inflammation, pain, and the immune system. So, this is the main way that CB2 oil works. CB2 comes and triggers these receptors to reduce pain while supporting the healthy immune response.

So, which conditions can CB2 help with? 

The research on β-Caryophyllene is pretty exciting. It shows promising benefits for numerous conditions where inflammation and immune dysregulation are key players, particularly with pain. However there are a myriad of other potential uses as well, including mental, gut and addictive issues.

  • Gut health – especially in Irritable Bowel Diseases
  • Arthritis and joint pain
  • Autoimmune diseases
  • Asthma and hayfever
  • Recurrent colds and flus
  • Chronic pain conditions
  • Muscles aches, spasms and pain
  • Reducing nicotine seeking behaviour in smokers
  • Anti-cancer effects
  • Reducing anxiety
  • Anti-inflammatory
  • Anti-bacterial

CB2 VS CBD: What’s the difference?

CBD and CB2 are closely related. However, CBD oil is a strictly monitored compound extracted from the hemp plant. This is only available through a prescription from GP’s that have gained CBD certification. Which has made it very difficult to access. While CBD also has promising research there is very little access currently in Australia. Therefore CB2 might be a great alternative.

The bottom line

The research shows that the benefits of CB2 are vast- from pain relief to anti-inflammation to immune support. We’re excited to see where the research goes with this one.

If you want to know more pop in and have a chat with one of our qualified staff or you can book a consult here.

Disclaimer: This site should not be used to diagnose, treat, prevent or cure any disease or condition. CB2 supplements are only intended for healthy adults, 15 years of age or older. Consult your medical practitioner before using any dietary supplement. Do not use if pregnant or nursing (breastfeeding).


  • The CB2receptor and its role as a regulator of inflammation
  • Daniel G Couch, PhD, Hollie Cook, Catherine Ortori, PhD, Dave Barrett, PhD, Jonathan N Lund, PhD, Saoirse E O’Sullivan, PhD, Palmitoylethanolamide and Cannabidiol Prevent Inflammation-induced Hyperpermeability of the Human Gut In Vitro and In Vivo—A Randomized, Placebo-controlled, Double-blind Controlled Trial, Inflammatory Bowel Diseases, Volume 25, Issue 6, June 2019, Pages 1006–1018,
  • Seltzer, E. S., Watters, A. K., MacKenzie, D., Jr, Granat, L. M., & Zhang, D. (2020). Cannabidiol (CBD) as a Promising Anti-Cancer Drug. Cancers12(11), 3203.
  • Boyaji, S., Merkow, J., Elman, R., Kaye, A. D., Yong, R. J., & Urman, R. D. (2020). The Role of Cannabidiol (CBD) in Chronic Pain Management: An Assessment of Current Evidence. Current pain and headache reports24(2), 4.
  • Shannon, S., Lewis, N., Lee, H., & Hughes, S. (2019). Cannabidiol in Anxiety and Sleep: A Large Case Series. The Permanente journal23, 18–041.